PCT / AI / SERM

Raloxifene

CAS 84449-90-1
Formula C₂₈H₂₇NO₄S
Half-life 27.7 hours (oral)

Chemical Identity

CAS Number	`84449-90-1`
IUPAC Name	[6-hydroxy-2-(4-hydroxyphenyl)-1-benzothiophen-3-yl]-[4-(2-piperidin-1-ylethoxy)phenyl]methanone
Molecular Formula	C₂₈H₂₇NO₄S
Molecular Weight	473.59 g/mol
SMILES	`OC1=CC=C(C=C1)C2=C(C3=CC(O)=CC=C3S2)C(=O)C4=CC=C(OCCN5CCCCC5)C=C4`
InChIKey	`GZUITABIAKMVPG-UHFFFAOYSA-N`
Melting Point	143-147 °C
Solubility	Practically insoluble in water; soluble in DMSO, methanol
Half-life	27.7 hours (oral)

Pharmacological Profile

Aromatisation	None
Hepatotoxicity	Low

Known trade names

Evista
Optruma
Raloxifene

External references

PubChem CID 5035
PubMed clinical literature
Wikipedia overview

Data sourced from peer-reviewed pharmacological literature and authoritative chemical databases (PubChem, DrugBank, ChEBI). Provided for identification and research reference only — not medical advice.