PCT / AI / SERM

Exemestane

  • CAS 107868-30-4
  • Formula C20H24O2
  • Half-life 24 hours (oral)
Chemical structure of Exemestane
PubChem CID 60198 ↗

Chemical Identity

CAS Number 107868-30-4
IUPAC Name (8R,9S,10R,13S,14S)-10,13-dimethyl-6-methylidene-7,8,9,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,17(4H)-dione
Molecular Formula C20H24O2
Molecular Weight 296.40 g/mol
SMILES C[C@]12CC[C@@H]3C(=CC(=O)C=C3[C@@H]1CCC2=O)C=C
InChIKey BFYIZQONLCFLEV-DAELLWKTSA-N
Melting Point 155-158 °C
Solubility Freely soluble in DMSO, methanol; practically insoluble in water
Half-life 24 hours (oral)

Pharmacological Profile

Aromatisation None
Hepatotoxicity Low

Known trade names

  • Aromasin
  • Exemestane Pfizer
  • Exetrol

External references

Data sourced from peer-reviewed pharmacological literature and authoritative chemical databases (PubChem, DrugBank, ChEBI). Provided for identification and research reference only — not medical advice.