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Anastrozole 1 mg Hilma Biocare

Hilma Biocare

70,00

In Stock (100 available)

Anastrozole 1 mg Hilma Biocare (1 mg) — Anastrozole is the most commonly prescribed aromatase inhibitor in both medical oncology and athletic performance contexts. By sel…

100 in stock

This product is for laboratory research use only. Not for human consumption.

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Description

Anastrozole 1 mg Hilma Biocare — anastrozole from Hilma Biocare at 1 mg. Reversible aromatase inhibitor with 46-hour half-life. EOD dosing with 500+ mg/week testosterone is a common starting point — adjust by E2 bloodwork, not symptoms alone.

Key Benefits

  • Aromatase inhibitor — blocks oestrogen synthesis at the source
  • Standard on-cycle AI for testosterone-based protocols
  • Low dose (0.25–0.5 mg EOD) typically sufficient for 400–500 mg test
  • Dose by bloodwork — sensitive E2 assay, target 20–40 pg/mL
  • Crashing E2 feels worse than mildly elevated E2 — err on the low side
  • Each unit dosed at 1 mg — see Recommended Dosage below for protocol-specific intake

Recommended Dosage

Research dosing: 0.25–0.5 mg every other day on testosterone-based cycles. Titrate to bloodwork (sensitive E2 assay, target 20–40 pg/mL). Higher doses required only on aggressive 700+ mg/week test protocols. During PCT: not used (blocks oestrogen needed for LH signalling).

How It Works

Non-steroidal aromatase inhibitor. Binds and inactivates the aromatase enzyme (CYP19A1) that converts testosterone and androstenedione to estradiol and estrone. Reversible binding — effect disappears within days of stopping.

Pharmacokinetics

Plasma half-life approximately 50 hours. Every-other-day dosing produces stable serum and tissue levels. Steady-state in 7 days.

Cycle & Stacking Guide

Used on-cycle with aromatising compounds (testosterone, methandienone, oxymetholone). Start at 0.25 mg EOD, bloodwork at week 4, adjust. Never used during PCT — needed estrogen signalling for LH/FSH recovery.

Manufacturer Notes

Hilma Biocare operates a Romanian GMP site with dedicated HPLC bays. Their catalogue emphasises clean oil carriers (often MCT or ethyl oleate) to reduce post-injection pain.

Storage & Handling

Store in the original blister or bottle at 15–25 °C, away from direct sunlight, heat, and humidity. Oral preparations lose potency faster if exposed to moisture; keep the desiccant (if included) with the tablets. Keep out of reach of children. For research and educational purposes only.

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Anastrozole

Physical & Chemical Properties for Research Purposes
Chemical structure of Anastrozole (C17H19N5) for laboratory analysis
2D structural representation · PubChem CID 2187 ↗
Chemical Identity
# CAS Registry Number 120511-73-1
Σ IUPAC Name 2-[5-(1H-1,2,4-triazol-1-ylmethyl)-2-methylphenyl]-2-methylpropanenitrile
F Molecular Formula C17H19N5
M Molecular Weight 293.37 g/mol
SMILES CC1=CC(=CC(=C1)C(C)(C)C#N)CN2C=NC=N2
InChIKey YBBLVLTVTVKRGT-UHFFFAOYSA-N
Melting Point 81-82 °C
Solubility Freely soluble in methanol, acetone; very slightly soluble in water
Biological Half-life 40-50 hours (oral)
PubChem CID 2187 ↗
Pharmacological Profile
Aromatization None
Hepatotoxicity Low

Clinical Notes

Third-generation non-steroidal aromatase inhibitor — competitive binding to CYP19A1 without receptor degradation. Dose-response is steep and individual: 0.25 mg twice weekly is a functional starting point on 500 mg/week testosterone protocols; 1 mg doses reliably crash E2 below physiological threshold in the majority of lean subjects. Half-life of 48 hours allows twice-weekly dosing. Clinical error pattern: aggressive preemptive dosing produces the hypoestrogenaemic profile (arthralgia, cognitive dulling, lipid degradation, libido crash) faster than a gradual increase ever produces gyno. Correct sequencing: bloodwork at week 4–5 of cycle, dose to measured E2 value, retest after 3 weeks. AI-free protocols are clinically viable for low-aromatiser users.

Known trade names: Arimidex, Anastrol, Armotraz

Data sourced from published pharmacological literature and authoritative chemical databases (PubChem, DrugBank, ChEBI). Provided for identification and research reference only.